Endocrine Abstracts

Adenomyosis is an oestrogen-dependent uterine disease where ectopic, non-neoplastic endometrium is histologically observed within the myometrium. Its incidence ranges between 5 and 70% and although presenting symptoms; menorrhagia (40–50%), dysmenorrhoea (10–30%) and metrorrhagia (10–12%) are well known, its aetiopathology remains unclear. The neurotrophin, nerve growth factor (NGF), has been implicated in the aetiopathology of adenomyosis, especially in the tam...